The event is the fourth annual Road2Recovery Charity Rideout, organised by paralysed fundraiser Claire Lomas.
The group will travel through Melton Mowbray, Oakham and Market Harborough before arriving for refreshments at Wistow Café around 1pm.
Proceeds will go to the Nicholls Spinal Injury Foundation, the Matt Hampson Foundation and The Bike Experience.
Claire said: “We are hoping for a good turnout again this year on what should be a sunny day.
“People can pre-register or register on the day.”
Those who want to take part can pre-register before 11pm tomorrow (Friday).
For a donation of £5, £10, £15 or £20, riders will also get an R2R Rideout lapel badge, pen and keyring.
Participants can also register before 9.30am on the day at the start at Eye Kettleby Lakes, where hot and cold drinks will be available.
A barbecue is planned at Wistow when the party arrives.
Go online to www.claireschallenge.co.uk to pre-register or to get more information on the event.
This year’s event is also in support of Claire’s challenge to complete a lap at nine circuits in the Bennetts British Superbikes series.