Three people were taken to hospital after an Audi and a Jaguar were in collision on the A606 between Melton and Oakham.
Two casualties had to be extricated by firefighters from the wreckage following the accident, which happened near Langham at around 1pm on Saturday.
A spokesperson for East Midlands Ambulance Service (EMAS) said: “A fast response vehicle attended the scene and immediately requested back-up from the air ambulance and double-crewed ambulances.
“Three people were taken to hospital and one was treated at the scene.”
Paramedics took two of the patients to Queen’s Medical Centre in Nottingham and the other to Leicester Royal Infirmary but the extent of their injuries is not known.
Rutland Police (@RutlandPolice) Tweeted shortly after the incident: “The A606 has now reopened, thankfully slight injuries only and two very mangled cars, the delays in reopening were caused by oil on the road!”
A spokesperson for Leicestershire Police said: “The casualties were taken to hospital as a precaution so we can assume they had only minor injuries.”
The road was blocked for two hours while the cars were made safe and investigations were carried out.